Recurrent Mastoiditis Mimics IgG4 Related Disease: A Potential Diagnostic Pitfall

Increased IgG4-Positive Plasma Cells in Granulomatosis with Polyangiitis: A Diagnostic Pitfall of IgG4-Related Disease

Granulomatosis with polyangiitis (Wegener's) (GPA) may mimic IgG4-related disease (IgG4-RD) on histologic examination of some biopsies, especially those from head and neck sites. IgG4 immunostain is often performed in this context for differential diagnosis with IgG4-RD. However, the prevalence of IgG4+ cells in GPA has not been explored. We examined the IgG4+ cells in 26 cases confirmed as GPA...

IgG4-Related Disease Presenting as Recurrent Mastoiditis With Central Nervous System Involvement

We report a case of a 43-year-old female who presented with right ear fullness and otorrhea. She was initially diagnosed with mastoiditis that was not responsive to multiple courses of antibiotics and steroids. She was then diagnosed with refractory inflammatory pseudotumor, and subsequent treatments included several mastoidectomies, further steroids, and radiation therapy. The patient went on ...

Recurrent pleuritis: consider IgG4-related systemic disease.

Diagnostic Value of Serum IgG4 for IgG4-Related Disease

Many studies about serum IgG4 for the diagnosis of IgG4-related disease (IgG4-RD) have been reported. However, these studies had relatively small sample sizes and the diagnostic accuracy values varied much between them.The aim of this study was to perform a meta-analysis to evaluate the diagnostic value of serum IgG4 for IgG4-RD.We conducted a search of relevant articles using MEDLINE, EMBASE, ...

Soft-tissue textiloma: a potential diagnostic pitfall.

Klippel–Trenaunay syndrome has 3 essential features: cutaneous hemangiomas, varicose veins and hypertophy of the involved limbs in length or girth, or both. Both bones and soft tissue are usually affected by the hypertrophy. The arteriovenous malformation effects are polysystemic. Patients with this syndrome are at risk of thromboembolic disease. Baskerville’s report shows that 7 (14%) of 49 pa...